姓名

陈霞

性别

女

专业技术职称

教授

学科专业

组织学与胚胎学

单  位

南通大学

电子邮箱

ylchenxia@ntu.edu.cn

联系电话（办公）

139****5629

0513-85051720

个人简历

博士，硕导，现任南通大学医学院组织学与胚胎学系主任。江苏省解剖学会理事会理事。主要从事脑缺血损伤病理机制与防治的研究。2011年作为访问学者至美国进修两年。主持和作为主要参与人完成市厅级及以上课题7项，以第一作者或通讯作者发表SCI论文十余篇。

研究领域

主要从事缺血性脑卒中病理机制与防治的研究，研究集中在相关蛋白和外泌体在脑缺血损伤中的作用及机制研究。

代表性成果（论文、专著、专利等）

(1) Deng A^#, Ma L, Ji Q, Xing J, Qin J, Zhou X, Wang X, Wang S, Wu J*, Chen X*. Activation of the Akt/FoxO3 signaling pathway enhancesoxidative stress-induced autophagy and alleviates brain damage in a rat model of ischemic stroke. Can J Physiol Pharmacol. 2023 Jan 1;101(1):18-26. Epub 2022 Oct 31.

(2) Deng A^#, Ma L^#, Zhou X, Wang X, Wang S, Chen X*. FoxO3 transcription factor promotes autophagy after oxidative stress injury in HT22 cells. Can J Physiol Pharmacol. 2021, 99(6):627-634.

(3) Zhou H^#, Wang X^#, Ma L, Deng A, Wang S, Chen X*. FoxO3 transcription factor promotes autophagy after transient cerebral ischemia/reperfusion. Int J Neurosci. 2018, 1-8. Int J Neurosci. 2019, 129(8):738-745.

(4) Li H^#, Wu Y, Suo G, Shen F, Zhen Y, Chen X*, Lv H*. Profiling neuron-autonomous lncRNA changes upon ischemia/reperfusion injury. Biochem Biophys Res Commun. 2018, 495(1):104-109.

(5) Shi J^#, Chen X^#*, Li H, Wu Y, Wang S, Shi W, Chen J, Ni Y*. Neuron-autonomous transcriptome changes upon ischemia/reperfusion injury. Sci Rep. 2017, 7(1):5800.

(6) Dai CL^#, Chen X^#, Kazim SF, Liu F, Gong CX, Grundke-Iqbal I, Iqbal K*. Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies. J Neural Transm (Vienna). 2015, 122(4):607-617.

(7) Chen X^#, Deng A^#, Zhou T, Ding F*. Pretreatment with 2-(4-methoxyphenyl) ethyl-2-acetamido-2-deoxy-β-D-pyranoside attenuates cerebral ischemia/reperfusion induced injury in vitro and in vivo. PLoS One. 2014, 9(7):e100126.

(8) Chen X^#*, Deng A^#, Zhou H, Gu J. Neuroprotective effect of 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxy-β-D-pyranoside against sodium nitroprusside-induced neurotoxicity in HT22 cells. Mol Cell Biochem. 2013, 383(1-2):149-159.

(9) Chen X, Liu, J, Gu, XS, Ding, F*. Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats.brain res. 2008,1238:189-198