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| 导师类别 | 博导 | 专业技术职称 | 教授 | |||||||
| 所在学科专业 | 医学生理学 | |||||||||
| 电子邮箱 | yhqiu@ntu.edu.cn | 联系电话 | 85051723 | |||||||
| 任职情况 | ||||||||||
| 主要研究方向 | 1. 神经内分泌免疫学 2. 神经内分泌递质与自身免疫性疾病 | |||||||||
| 个人简历 | 1994.12－2000.05 原南通医学院 生理学系 副教授 2000.02－2003.12 南京大学 生理学专业 博士研究生/博士学位 2005.10－2013.03 南通大学科技处 副处长 2012.06－2012.09 澳大利亚La Trobe大学 访问学习 2014.06－2014.09 英国莱斯特大学 访问学习 2000.06－至今 南通大学医学院 生理学系 教授 2000.07－至今 南通大学医学院 生理学系 主任 | |||||||||
| 学术成果 | 发表的SCI论文目录（第一作者或通讯作者）： 1.Qiu YH, Peng YP, Wang JH. Immunoregulatory role of neurotransmitters. Advances in Neuroimmunology. 1996；6: 223-231. 2.Qiu YH, Peng YP, Jiang JM, Wang JJ. Expression of tyrosine hydroxylase in lymphocytes and effect of endogenous catecholamines on lymphocyte function. Neuroimmunomodulation, 2004; 11: 75-83. 3.Qiu YH, Peng YP, Jiang JL, Wang JJ. Effect of acetylcholine on in vitro IL-2 production and NK cell cytotoxicity of rats. Lymphology, 2004; 37: 31-38. 4.Qiu YH, Cheng C, Dai L, Peng YP. Effect of endogenous catecholamines in lymphocytes on lymphocyte function. J Neuroimmunol, 2005; 167: 45-52. 5.Peng YP, Qiu YH*, Qiu J, Wang JJ. Cerebellar interposed nucleus lesions suppress lymphocyte function in rats. Brain Research Bulletin, 2006; 71：10-17. 6.Jiang JL, Peng YP, Qiu YH*, Wang JJ. Effect of endogenous catecholamines on apoptosis of Con A-activated lymphocytes of rats. J Neuroimmunol, 2007；192: 79-88. 7.Wang XQ , Peng YP, Lu JH, Cao BB, Qiu YH*. Neuroprotection of Interleukin-6 Against NMDA Attack and Its Signal Transduction by JAK and MAPK. Neurosci Lett, 2009；450: 122-126. 8.Jiang JL, Peng YP, Qiu YH*, Wang JJ. Adrenoreceptor-Coupled Signal-Transduction Mechanisms Mediating Lymphocyte Apoptosis Induced by Endogenous Catecholamines. J Neuroimmunol, 2009；213: 100-111. 9.Ni SJ, Qiu YH*, Lu JH, Cao BB, Peng YP. Effect of Cerebellar Fastigial Nuclear Lesions on Differentiation and Function of Thymocytes. J Neuroimmunol, 2010；222：40-47. 10.Xiao J, Huang HW, Peng YP, Bao JY, Huang Y, Qiu YH*. Modulation of Natural Killer Cell Function by ？-Adrenoreceptor-Coupled Signalling. Neuroendocrinol Lett, 2010; 31: 635-644. 11.Huang Y, Qiu AW, Peng YP, Liu Y, Huang HW, Qiu YH*. Roles of Dopamine Receptor Subtypes in Mediating Modulation of T Lymphocyte Function. Neuroendocrinol Lett, 2010; 31: 782-791. 12.Liu Z, Qiu YH*, Li B, Ma SH, Peng YP. Neuroprotection of Interleukin-6 Against NMDA-Induced Apoptosis and Its Signal-Transduction Mechanisms. Neurotoxicity Res, 2011; 19:484–495. 13.Wang F, Cao BB, Qiu YH*, Liu Y, Huang Y, Peng YP. Role of Cerebellohypothalamic GABAergic Projection in Mediating Cerebellar Immunomodulation. Int J Neurosci, 2011; 121: 237-245. 14.Sun XM, Lua JH, Qiu YH*, Liu Z, Wang XQ, Peng YP. Interleukin-6 Reduces NMDA-Induced Ca2+ Overload via Prevention of Ca2+ Release from Intracellular Store. Int J Neurosci, 2011; 121: 423-429. 15.Lu JH, Mao HN, Cao BB, Qiu YH*, Peng YP. Effect of Cerebellohypothalamic Glutamatergic Projections on Immune Function. Cerebellum, 2012; 11: 905-916. 16.Ma SH, Li B, Huang HW, Peng YP, Qiu YH*. Interleukin-6 Inhibits L-type Calcium Channel Activity of Cultured Cerebellar Granule Neurons. J Physiol Sci, 2012; 62: 385-392. 17.Cao BB, Han XH, Huang Y, Qiu YH*, Peng YP. The hypothalamus mediates the effect of cerebellar fastigial nuclear glutamatergic neurons on humoral immunity. Neuroendocrinol Lett, 2012; 33: 393-400. 18.Liu Y, Huang Y, Wang XQ, Peng YP, Qiu YH*. Effects of Tyrosine Hydroxylase Gene Silencing in CD4+ T Lymphocytes Differentiation and Function of Helper T Cells. Neuroendocrinol Lett, 2012; 33: 643-650. 19.Cao BB, Huang Y, Lu JH, Xu FF, Qiu YH*, Peng YP. Cerebellar fastigial nuclear GABAergic projections to the hypothalamus modulate immune function. Brain Behav. Immun, 2013; 27: 80-90. 20.Fang XX, Jiang XL, Han XH, Peng YP, Qiu YH*. Neuroprotection of interleukin-6 Against NMDA-Induced Neurotoxicity is Mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT Signaling Pathways. Cell Mol Neurobiol, 2013; 33: 241-251. 21.Huang HW, Tang JL, Han XH, Peng YP, Qiu YH*. Lymphocyte-Derived Catecholamines Induce a Shift of Th1/Th2 Balance toward Th2 Polarization. Neuroimmunomodulation, 2013; 20: 1-8. 22.Liu Z, Fang XX, Chen YP, Qiu YH*, Peng YP. Interleukin-6 Prevents NMDA-Induced Neuronal Ca2+ Overload via Suppression of IP3 Receptors. Brain Inj, 2013; 27：1047-1055. 23.Zhao XY, Cui SW, Wang XQ, Peng YP, Qiu YH*. Tyrosine hydroxylase expression in CD4+ T cells is associated with anti-inflammatory mechanism in collagen type II-induced arthritis. Rheumato Int, 2013; 33：2597-2605. 24.Zhao W, Huang Y, Liu Z, Cao BB, Peng YP, Qiu YH*. Dopamine Receptors Modulate Cytotoxicity of Natural Killer Cells via cAMP-PKA-CREB Signaling Pathway. PLOS ONE, 2013; 8：e65860. 25.Zhang J, Keb KF, Liu Z, Qiu YH*, Peng YP. Th17 cell-mediated neuroinflammation is involved in neurodegeneration of Aβ1-42-induced Alzheimer’s disease model rats. PLOS ONE, 2013; 8：e75786. 26.Xu FF, Huang Y, Wang XQ, Qiu YH*, Peng YP. Modulation of immune function by glutamatergic neurons in the cerebellar interposed nucleus via hypothalamic sympathetic pathways. Brain Behav. Immun, 2014; 38: 263-271. 27.Shen WX, Chen JH, Lu JH, Peng YP, Qiu YH*. TGF-β1 Protection Against Aβ1-42-Induced Neuroinflammation and Neurodegeneration in Rats. Int. J. Mol. Sci, 2014; 15: 22092-22108. 28.Huang HW, Fang XX, Wang XQ, Peng YP, Qiu YH*. Regulation of Differentiation and Function of Helper T Cells by Lymphocyte-Derived Catecholamines via α1-and β2-Adrenoceptors. Neuroimmunomodulation, 2015; 22: 138-151. 29.Cao BB, Huang Y, Jiang YY, Qiu YH*, Peng YP. Cerebellar Fastigial Nuclear Glutamatergic Neurons Regulate Immune Function via Hypothalamic and Sympathetic Pathways. J Neuroimmune Pharmacol, 2015; 10: 162-178. 30.Chen JH, Ke KF, Lu JH, Qiu YH*, Peng YP. Protection of TGF-β1 against Neuroinflammation and Neurodegeneration in Aβ1-42-Induced Alzheimer’s Disease Model Rats. PLOS ONE, 2015; DOI: 10.1371/journal.pone.0116549. 31.Lu JH, Wang XQ, Huang Y, Qiu YH*, Peng YP. GABAergic neurons in cerbellar interposed nucleus modulate cellular and humoral immunity via hypothalamic and sympathetic pathways. J Neuroimmunol, 2015; 283: 30-38. 32.Ma SH, Zhuang QX, Shen WX, Peng YP, Qiu YH*. Interleukin-6 reduces NMDAR-mediated cytosolic Ca2+ overload and neuronal death via JAK/CaN signaling. Cell Calcium, 2015; 58: 286-295. 33.Jiang YY, Cao BB, Wang XQ, Peng YP, Qiu YH*. Cerebellar ataxia induced by 3-AP affects immunological function. Neuroendocrinol Lett, 2015; 36: 246-256. 34.Liu Z, Chen HQ, Huang Y, Qiu YH*, Peng YP. Transforming growth factor-β1 acts via TβR-I on microglia to protect against MPP+-induced dopaminergic neuronal loss. Brain Behav Immun. 2015; doi: 10.1016/j.bbi.2015.08.006. 35.Lu JH, Liu YQ, Deng QW, Peng YP, Qiu YH*. Dopamine D2 receptor is involved in alleviation of type II collagen-induced arthritis in mice. Biomed Res Int, in press. 36.Huang HW, Zuo C, Chen X, Peng YP, Qiu YH*. Effect of Tyrosine Hydroxylase Overexpression in Lymphocytes on Differentiation and Function of Helper T Cells. Int J Mol Med, in press. 出版的著作目录： 1.邱一华（副主编）：生理学，东南大学出版社，2000.07，书号：ISBN 7-81050-107-0。 2.邱一华（主编）：生理学，科学出版社，2013.01，书号：ISBN 978-7-03-036286-5。 3.邱一华（参编）：医学生理学，北京大学医学出版社，2013.12，书号：ISBN 978-7-5659-0708-1。 授权的发明专利目录： 1.邱一华等：实验小动物脑切面校正器，2013.05。 2.邱一华等：能与多种立体定位仪匹配使用的角度校正器，2013.08。 3.邱一华等：在高效液相色谱仪恒温箱中使用的色谱柱温度均匀器，2014.05。 4.邱一华等：多根不同长度色谱柱为一体的温度均匀器，2014.08。 5.邱一华等：帮助电极准确倾斜导入的角度校正器，2014.11。 6.邱一华等：工作温度稳定、均匀的色谱柱温度均匀器，2014.09。 7.邱一华等：保持色谱柱工作温度均匀的温度均匀器，2015.04。 8.邱一华等：色谱柱温度均匀器的使用方法，2015.05。 9.邱一华等：结构合理的立体定位仪用角度校正器，2015.07。 10.邱一华等：省略繁琐计算的立体定位仪用角度校正器, 2015.10。 | |||||||||
| 获奖情况 | 1.2009年被评为江苏省优秀教育工作者 2.2005年被评为江苏省高校优秀共产党员标兵 3.1999年获江苏省普通高等学校“红杉树”园丁奖 银奖 4.2011年获江苏省科学技术二等奖（排名第3） 5.1999年获交通部科学技术进步三等奖（排名第1） 6.2012年主讲的医学生理学被评为江苏省优秀研究生课程 7.2012年被评为南通市杰出专业技术人才 8.2008年被评为南通市优秀科技工作者 9.2003年被授予南通市五一奖章 10.2001年被评为南通市专业技术拔尖人才 | |||||||||
| 主要科研项目 | 1.国家自然科学基金面上项目（主持）：儿茶酚胺对类风湿性关节炎Treg/Th17失衡的作用及其受体信号转导机制，项目编号：31371182。 2.国家自然科学基金面上项目（第二）：Treg/Th17失衡介导的神经炎症在帕金森病发病机制中的作用，项目编号：81271323。 | |||||||||
| 备注 | 现担任的学术职务： 1.江苏省生理科学学会常务理事； 2.中国生理学会应激专业委员会委员； 3.中国生理学会内分泌代谢专业委员会副主任委员 | |||||||||